Hospitalization in COVID-19 Breakthrough Cases Countless studies have proven that one of the most important forms of protection from COVID-19 infection is vaccination. As of Sep 21, 2021 54.8% of Americans and 64.5% of people who are age 12 and above are fully vaccinated. While the chances of COVID-19 infection after vaccination are significantly reduced, there have been reports of rare cases of SARS-CoV-2 breakthrough infection in fully vaccinated individuals. (See COVID-19 Breakthrough Infections ) Previous studies have found that the viral load of an individual with a COVID-19 breakthrough infection is not significantly different than that of an individual who is unvaccinated. (See Can Vaccination Reduce COVID-19 Transmission? ) However, more questions related to breakthrough infections have arisen including whether or not a vaccinated individual with COVID-19 has a reduced risk of severe illness and hospitalization. A study published in The Lancet in September 2021 collected
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